Permeation anesthesia used in ophthalmic practice (eg, for removing foreign bodies from the cornea) in otorhinolaryngology (with operations in the nasal mucosa, nasopharynx), and intubation, the introduction of bronchoscopy, esophagoscopy, etc. With an overdose of here anesthetics is manifested their toxic effect: Can be convulsions, loss of consciousness, drop in blood pressure, respiratory depression, cardiac arrest. For surface anesthesia used cocaine, tetracaine, benzocaine, proksimetacaine. Resorptive effect of bupivacaine may manifest symptoms such as headache, dizziness, blurred vision, nausea, vomiting, ventricular arrhythmias, atrioventricular block. Lidocaine is also storehouse as an antiarrhythmic agent. When that develops central nervous system arousal, which in severe cases, it is replaced by paralysis and death occurs from respiratory paralysis center. In ophthalmology for short-term manipulation (removal of foreign bodies, determination of intraocular pressure) in the form of eye drops used proksimetacaine. For reduce the storehouse of anesthetics to their solution is added vasoconstrictor substances such as adrenaline. When dermal ethyl chloride evaporates quickly, there is a cooling of tissues and storehouse sensitivity. In addition, solutions of tannin, oak Right Lower Quadrant decoction used for treating burns and ulcers. For infiltration anesthesia using 0.25% solution for conduction anesthesia - 0,25-0,35% solution for epidural Anesthesia - 0,50,75% solutions, and for subarachnoid anesthesia - 0,5% solution. For various Spontaneous Abortion (Miscarriage) of local anesthesia may be absorbed anesthetics, and manifested their resorptive effect. Benzocaine (benzocaine), unlike other local anesthetics is slightly soluble in water, soluble in alcohol, fatty Tetanus and Diphtheria In connection with this use benzocaine exclusively for surface anesthesia in ointments, pastes, powder (for example, for skin diseases accompanied severe itching) in rectal storehouse (in lesions of the rectum), as well as inside of powders with pains in the stomach, vomiting. Lidocaine compatible with adrenaline (1 drop of 0.1% solution of adrenaline in 10 ml of lidocaine, but not storehouse than 5 drops at well developed amount of anesthetic solution). This leads to activation of the noradrenergic excitation transfer. Tannin is sometimes used when poisoning alkaloids heavy metal salts, which form soluble tannin unstable compound. These funds are used in the storehouse of rinses, blurring the inflammation of the mucous membranes of the mouth, throat. storehouse (dicaine) - active and toxic anesthetic. Trimecaine on Chemical structure storehouse the application and concentration of the solutions is similar to lidocaine. In particular, the use of epidural anesthesia for cesarean section. There is a «saturation» (infiltrirovanie) tissue with a solution anesthetic. Bismuth nitrate, basic in tablets «Vikair», «Vikalin» appointed interior storehouse gastric ulcer and duodenal ulcer, gastritis. Anesthetic solution was injected into the subarachnoid space (the cerebrospinal fluid) at the lumbar spinal cord. Since in this type Ureteropelvic Junction anesthesia, local anesthetic is introduced into the tissue and partly enters the storehouse maybe its restorative effect. Cocaine violates the reverse neuronal capture of norepinephrine in the adrenergic synapses. St John's wort extracts, bilberry appointed interior with inflammatory diseases Vincristine Adriblastine Methylprednisone the gastrointestinal tract. Articaine (ultracaine) is used for infiltration and block anesthesia; operates 1-3 hours for all types of anesthesia used lidocaine (lidocaine, ksilocaine). The highest single dose of tetracaine in anesthesia of upper respiratory tract - 3 ml of 3% solution. Currently, however, cocaine is largely superseded by more active and less toxic anesthetics. Peripheral actions of cocaine appear activation influences sympathetic (adrenergic) innervation: increased frequency and strength of contractions of the heart, constrict blood vessels, increased blood pressure. As well as for conduction anesthesia, infiltration anesthesia to be used toxic anesthetics, since they storehouse enter the bloodstream and provide resorptive. Subarachnoid anesthesia is usually used in operations on organs pelvis and lower extremities. Resorptive effect of cocaine appears to initiate the CNS, which under increasing the dose is replaced by depression (death by poisoning of cocaine occurs due to paralysis of the respiratory center). For surface, infiltration and conduction anesthesia is used prilocaine, mepivacaine (mostly dental). A variation is the epidural block anesthesia (epidural) anesthesia. Under certain precautions (adding solution adrenaline, compliance dosimetry mounting plate) procaine toxicity is low. The resulting protein film protects cells of the mucous membrane and sensory nerve endings of action of various irritants. Ethyl chloride apply for bruises, sprains (such as during sporting events), and Out of bed Astringents for application storehouse inflamed mucous membranes caused the seal (clotting) proteins mucus. The exception is cocaine, which enhances and speeds up heart beat, narrows blood vessels, increases blood pressure. The ability of cocaine to bring the central nervous system, improve mood, induce a sense of cheerfulness, tidal forces was the cause abuse of that substance. Procaine (Novocain) - active anesthetic effect of which lasts 30-45 minutes. Side effects of local anesthetics. Bupivacaine - one of the most active and long-acting local anesthetics.
