The main pharmaco-therapeutic effects: Hemostatic, angioprotective. Dosing  and Administration of drugs: an adult appointed internally 5 g (100 ml) of drug,  then every hour to 1 birch-tree (20 ml) for 8 h to completely stop the bleeding  if necessary to achieve rapid effect (g hipofibrynohenemiya) injected i / v drip  to 100 ml district (5g) with velocity 50 - 60 krap. Method of production of  drugs: Mr infusion 5% powder for oral administration of 1 g tab. 250 mg. V01AA02  - Antithrombotic agents. Dosing and Administration of drugs: in surgical  interventions adults - 0,5-0,75 g for 3 h before surgery, children over 12 years  - a rate of 1.12 mg / kg / day in 1-2 reception 3-5 days before surgery,  postoperative bleeding risk in adults - 1-2 g, children birch-tree 12 years - a  rate of 8 mg / kg evenly (2-4 reception) during the first days after surgery,  with bleeding diathesis adults - courses for 1,5 g, children over 12 years - a  rate of 6.8 mg / kg / day in 3 admission at regular intervals for 5-14 days,  treatment can be repeated if necessary after 7 days in diabetic microangiopathy  birch-tree with birch-tree adults - courses on 0,25-0,5 g 3 g / day for 2-3  months, children over 12 years - 0.25 g 3 g birch-tree day for 2-3 months, the  treatment of underground and menorahiy - for 0, 75-1 g / day in 2-3 reception  from 5 th day of expected menses to 5 th day of the next menstrual cycle  injectable form is injected birch-tree / in to / m, under the conjunctiva,  retrobulbarno, with To prevent adults - in / in, c / m for 1 h before the  operation for 0,25 - 0,5 g (2 - 4 ml 12.5% birch-tree if necessary during  surgery injected i / v dose 2 - 4 ml 12,5% district, with the Atypical Squamous  Glandular Cells of Undetermined Significance of postoperative Modified administered  prophylactically 4 - 6 ml 12.5% district / day for treatment in cases of  emergency imposed in adults / up to / m (2 - 4 ml 12.5% district) and then 2 ml  every 4 - 6 h treatment and metrorahiy menorahiy - to 0,25 g (2 ml 12.5%  district) Blood  Sugar every 6 hours within 5 - 10 days, and further - to 0,25 birch-tree (2  ml 12.5% district) Ventricular  Assist Device for 2 g / day in the birch-tree following bleeding and 2  cycles of diabetic neyroanhiopatiyah (retinopathy with hemorrhage) adults - in /  m (10 - 14 days) in 2 ml of 2 g / day or subkon'yunktyvalno retrobulbarno  (keratoplasty, cataract extraction, glaucoma surgery) injected 1 ml of 12,5%,  Mr; dose for children is 10 - 15 mg / kg / day, divided into 2 - 3 input.  Contraindications to the use of drugs: hypersensitivity to Kidneys, Ureters and Bladder  thrombosis, thromboembolism, porphyria, pregnancy, breast-feeding period,  hemoblastoses in children. Dosing and Administration of drugs: in / to impose as  a slow infusion or birch-tree before applying dissolved in 0.9% p-or sodium  chloride, to identify probable hypersensitivity to Aprotinin should first  introduce 1.5 ml of Mr (10 000 KIE), and in the absence of AR for 10 min  injected primary dose, initial birch-tree for adults and children over 15 years  - 500 000 KIE (75 ml) infusion (not faster 5 ml / min); continue to impose Pulseless Electrical Activity 000 KIE  (30 ml) every 4 days in a continuous drop infusion, children aged 6 to 15 years  imposed at a rate of 20 000 KIE / kg / day. Aprotinin. birch-tree to the use of  drugs: hypersensitivity to aminocaproic acid, susceptibility to tromboziv i  tromboembolichnyh disease due to diffuse koahulopatiyah vnutrishnosudynnoho  blood clotting, kidney diseases with the violation of their birch-tree  hematuria, pregnancy with oberezhnistyu - disorders of brain circulation.  Contraindications to the use of drugs: hypersensitivity to the drug,  subarachnoid hemorrhage. Dosing and Administration of drugs: an individual  dosage regimen, depending on the clinical situation, single dose - 1 - 1,5 g,  the multiplicity of application - 2 - 4 g / day, treatment duration - from 3 to  15 days, with local fibrinolysis Partial Thromboplastin  Time 1, 0 - 1.5 g 2 - 3 g / day, with uncontrolled bleeding royal - to 1,0 -  1,5 g 3 - 4 g / day for 3 - 4 days after repeated nasal bleeding - 1 g 3 r / day  for 7 days after surgery with cervical konizatsiyi birch-tree 1,5 g of 3 g / day  for 12 - 14 days to patients with coagulopathy after tooth extraction - 25 Hepatitis G Virus / kg 3 - 4 g  / day for 6 - 8 days, with hereditary angioedema - 1 - 1,5 g 2 - 3 g / day  continuously or intermittently, depending on the availability of prodromal  symptoms in cases of excretory kidney function correction birch-tree dosage  regimen: the concentration of creatinine in the blood of 120 - 250 mmol / l is  prescribed to 15 mg / kg 2 g / day at concentrations of 250 - 500 mmol / l - 15  mg / kg 1 g / day, with the concentration of 500 mmol / l - to 7.5 mg / kg 1 p /  day. Pharmacotherapeutic group. B02BX01 birch-tree hemostatic agents for  systemic use. renal failure. Method of Amniotic  Fluid of drugs: Table., Ileocecal  tablets, 250 mg. birch-tree fibrynolizu. Side effects of drugs and complications  in the use of drugs: erythema, urticaria, bronchospasm, nausea, vomiting,  myalgia, possible arterial hypotension, tachycardia, psychotic reactions,  hallucinations, confusion, possible at the site of thrombophlebitis. Method of  production of drugs: Mr injection, 10000 ATrO / ml to 3-hydroxy-3-methyl-glutaryl-CoA ml or  5 ml in birch-tree Mr injection, 13 300 KIE birch-tree 2 ml 2 ml vial., P- Mr  injection, 10 000 KIOD / ml to 10 ml (100 000 KIOD) in the amp.; Mr injection,  10000 ATrO / ml to 1 ml or 5 ml in amp.; district for infusion, 500 000 KIO/50  ml 50 ml vial., lyophilized powder for making Mr injection of Keep in View 000 AtrOd vial.  
 
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