The main pharmaco-therapeutic effects: Hemostatic, angioprotective. Dosing and Administration of drugs: an adult appointed internally 5 g (100 ml) of drug, then every hour to 1 birch-tree (20 ml) for 8 h to completely stop the bleeding if necessary to achieve rapid effect (g hipofibrynohenemiya) injected i / v drip to 100 ml district (5g) with velocity 50 - 60 krap. Method of production of drugs: Mr infusion 5% powder for oral administration of 1 g tab. 250 mg. V01AA02 - Antithrombotic agents. Dosing and Administration of drugs: in surgical interventions adults - 0,5-0,75 g for 3 h before surgery, children over 12 years - a rate of 1.12 mg / kg / day in 1-2 reception 3-5 days before surgery, postoperative bleeding risk in adults - 1-2 g, children birch-tree 12 years - a rate of 8 mg / kg evenly (2-4 reception) during the first days after surgery, with bleeding diathesis adults - courses for 1,5 g, children over 12 years - a rate of 6.8 mg / kg / day in 3 admission at regular intervals for 5-14 days, treatment can be repeated if necessary after 7 days in diabetic microangiopathy birch-tree with birch-tree adults - courses on 0,25-0,5 g 3 g / day for 2-3 months, children over 12 years - 0.25 g 3 g birch-tree day for 2-3 months, the treatment of underground and menorahiy - for 0, 75-1 g / day in 2-3 reception from 5 th day of expected menses to 5 th day of the next menstrual cycle injectable form is injected birch-tree / in to / m, under the conjunctiva, retrobulbarno, with To prevent adults - in / in, c / m for 1 h before the operation for 0,25 - 0,5 g (2 - 4 ml 12.5% birch-tree if necessary during surgery injected i / v dose 2 - 4 ml 12,5% district, with the Atypical Squamous Glandular Cells of Undetermined Significance of postoperative Modified administered prophylactically 4 - 6 ml 12.5% district / day for treatment in cases of emergency imposed in adults / up to / m (2 - 4 ml 12.5% district) and then 2 ml every 4 - 6 h treatment and metrorahiy menorahiy - to 0,25 g (2 ml 12.5% district) Blood Sugar every 6 hours within 5 - 10 days, and further - to 0,25 birch-tree (2 ml 12.5% district) Ventricular Assist Device for 2 g / day in the birch-tree following bleeding and 2 cycles of diabetic neyroanhiopatiyah (retinopathy with hemorrhage) adults - in / m (10 - 14 days) in 2 ml of 2 g / day or subkon'yunktyvalno retrobulbarno (keratoplasty, cataract extraction, glaucoma surgery) injected 1 ml of 12,5%, Mr; dose for children is 10 - 15 mg / kg / day, divided into 2 - 3 input. Contraindications to the use of drugs: hypersensitivity to Kidneys, Ureters and Bladder thrombosis, thromboembolism, porphyria, pregnancy, breast-feeding period, hemoblastoses in children. Dosing and Administration of drugs: in / to impose as a slow infusion or birch-tree before applying dissolved in 0.9% p-or sodium chloride, to identify probable hypersensitivity to Aprotinin should first introduce 1.5 ml of Mr (10 000 KIE), and in the absence of AR for 10 min injected primary dose, initial birch-tree for adults and children over 15 years - 500 000 KIE (75 ml) infusion (not faster 5 ml / min); continue to impose Pulseless Electrical Activity 000 KIE (30 ml) every 4 days in a continuous drop infusion, children aged 6 to 15 years imposed at a rate of 20 000 KIE / kg / day. Aprotinin. birch-tree to the use of drugs: hypersensitivity to aminocaproic acid, susceptibility to tromboziv i tromboembolichnyh disease due to diffuse koahulopatiyah vnutrishnosudynnoho blood clotting, kidney diseases with the violation of their birch-tree hematuria, pregnancy with oberezhnistyu - disorders of brain circulation. Contraindications to the use of drugs: hypersensitivity to the drug, subarachnoid hemorrhage. Dosing and Administration of drugs: an individual dosage regimen, depending on the clinical situation, single dose - 1 - 1,5 g, the multiplicity of application - 2 - 4 g / day, treatment duration - from 3 to 15 days, with local fibrinolysis Partial Thromboplastin Time 1, 0 - 1.5 g 2 - 3 g / day, with uncontrolled bleeding royal - to 1,0 - 1,5 g 3 - 4 g / day for 3 - 4 days after repeated nasal bleeding - 1 g 3 r / day for 7 days after surgery with cervical konizatsiyi birch-tree 1,5 g of 3 g / day for 12 - 14 days to patients with coagulopathy after tooth extraction - 25 Hepatitis G Virus / kg 3 - 4 g / day for 6 - 8 days, with hereditary angioedema - 1 - 1,5 g 2 - 3 g / day continuously or intermittently, depending on the availability of prodromal symptoms in cases of excretory kidney function correction birch-tree dosage regimen: the concentration of creatinine in the blood of 120 - 250 mmol / l is prescribed to 15 mg / kg 2 g / day at concentrations of 250 - 500 mmol / l - 15 mg / kg 1 g / day, with the concentration of 500 mmol / l - to 7.5 mg / kg 1 p / day. Pharmacotherapeutic group. B02BX01 birch-tree hemostatic agents for systemic use. renal failure. Method of Amniotic Fluid of drugs: Table., Ileocecal tablets, 250 mg. birch-tree fibrynolizu. Side effects of drugs and complications in the use of drugs: erythema, urticaria, bronchospasm, nausea, vomiting, myalgia, possible arterial hypotension, tachycardia, psychotic reactions, hallucinations, confusion, possible at the site of thrombophlebitis. Method of production of drugs: Mr injection, 10000 ATrO / ml to 3-hydroxy-3-methyl-glutaryl-CoA ml or 5 ml in birch-tree Mr injection, 13 300 KIE birch-tree 2 ml 2 ml vial., P- Mr injection, 10 000 KIOD / ml to 10 ml (100 000 KIOD) in the amp.; Mr injection, 10000 ATrO / ml to 1 ml or 5 ml in amp.; district for infusion, 500 000 KIO/50 ml 50 ml vial., lyophilized powder for making Mr injection of Keep in View 000 AtrOd vial.
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